Impact of continuous glucose monitoring in youth with type 1 diabetes aged 15-21 years

Intern Med J. 2023 Feb;53(2):209-215. doi: 10.1111/imj.15347. Epub 2022 May 31.

Abstract

Background: People with type 1 diabetes (T1D) aged <21 years are eligible for subsidised continuous glucose monitoring (CGM) products under the Australian National Diabetes Services Scheme. There are few real-world published studies to evaluate the benefits of CGM in young adults.

Aims: To perform a real-world observation study among youth with T1D to evaluate CGM use and benefits of CGM.

Methods: Patients at the Westmead Hospital Young Adult Diabetes Clinic aged 15-21 years who commenced CGM before July 2018 were followed for 6 months post commencement of CGM. Differences in HbA1c and glucose metrics at baseline and follow up are compared between those commencing CGM and those that did not.

Results: Forty-four (38%) of 115 eligible patients commenced CGM. Demographic characteristics and baseline HbA1c did not differ significantly between those started on CGM and those that did not. At 6 months, 18 (41%) of 44 patients still used CGM, with discomfort and inconvenience the most common reasons for dropout. In CGM continuers, at 6 months compared with baseline, there was no change in HbA1c (8.2% vs 8.0%; P = 0.8), coefficient of variation of glucose (38% vs 39%; P = 0.5) or percentage time in range (52% vs 58%; P = 0.3). Six-month follow-up HbA1c in CGM non-users deteriorated significantly compared with users. Mean hypoglycaemia fear scores (worry scale) were significantly decreased from baseline at 6 months (33 vs 18; P < 0.01).

Conclusion: There are high rates of discontinuation in CGM use among youth with T1D. At 6 months of CGM use, there was no significant change in glycaemic control, although HbA1c in non-users deteriorated significantly. Worry of hypoglycaemia was significantly decreased among those who continued CGM.

Keywords: continuous glucose monitoring; type 1 diabetes; young adult; youth.

Publication types

  • Observational Study

MeSH terms

  • Adolescent
  • Australia
  • Blood Glucose
  • Blood Glucose Self-Monitoring
  • Diabetes Mellitus, Type 1* / diagnosis
  • Glycated Hemoglobin
  • Humans
  • Hypoglycemia* / diagnosis
  • Hypoglycemic Agents
  • Young Adult

Substances

  • Blood Glucose
  • Glycated Hemoglobin
  • Hypoglycemic Agents