The powerful symbiosis between synthetic and medicinal chemistry

Stefan Schiesser; Rhona J Cox; Werngard Czechtizky

doi:10.4155/fmc-2021-0062

The powerful symbiosis between synthetic and medicinal chemistry

Future Med Chem. 2021 Jun;13(11):941-944. doi: 10.4155/fmc-2021-0062. Epub 2021 Apr 21.

Authors

Stefan Schiesser¹, Rhona J Cox², Werngard Czechtizky¹

Affiliations

¹ Department of Medicinal Chemistry, Research & Early Development, Respiratory & Immunology (R&I), BioPharmaceuticals R&D, AstraZeneca, Pepparedsleden 1, 43183, Mölndal, Sweden.
² Department of Medicinal Chemistry, Research & Early Development, Cardiovascular, Renal & Metabolism, BioPharmaceuticals R&D, AstraZeneca, Pepparedsleden 1, 43183, Mölndal, Sweden.

PMID: 33878945
DOI: 10.4155/fmc-2021-0062

No abstract available

Keywords: BCP; bioisostere; bridged bicycle; intellectual property; medicinal chemistry; phosphine oxide; physicochemical properties; sulfoximine; synthesis; trifluoromethyl.

Publication types

Editorial

MeSH terms

Chemistry, Pharmaceutical*
Humans
Molecular Structure
Small Molecule Libraries / chemical synthesis
Small Molecule Libraries / chemistry
Small Molecule Libraries / pharmacology*

Substances

Small Molecule Libraries