Stir it up: The role of actin in mitochondrial mixing during mitosis

Sarah E Yde; Rachel S Kadzik; David R Kovar

doi:10.1016/j.devcel.2021.03.028

Stir it up: The role of actin in mitochondrial mixing during mitosis

Dev Cell. 2021 Apr 19;56(8):1080-1082. doi: 10.1016/j.devcel.2021.03.028.

Authors

Sarah E Yde¹, Rachel S Kadzik¹, David R Kovar²

Affiliations

¹ Department of Molecular Genetics and Cell Biology, University of Chicago, Chicago, IL 60637, USA.
² Department of Molecular Genetics and Cell Biology, University of Chicago, Chicago, IL 60637, USA; Department of Biochemistry and Molecular Biology, University of Chicago, Chicago, IL 60637, USA. Electronic address: drkovar@uchicago.edu.

PMID: 33878298
DOI: 10.1016/j.devcel.2021.03.028

Abstract

During symmetric cell division, it is important that daughter cells receive not only equal genetic information, but also equal allocations of organelles. Recently, in Nature,Moore et al. (2021) identify three complementary F-actin networks that help ensure proper mixing and distribution of functionally equivalent mitochondria to daughter cells.

Publication types

Comment

MeSH terms

Actin Cytoskeleton
Actins*
Mitochondria
Mitosis*
Organelles

Substances

Actins