Phialemonium obovatum Infection of the Renal Allograft: Case Report and Review of the Literature

Exp Clin Transplant. 2021 Aug;19(8):871-876. doi: 10.6002/ect.2020.0313. Epub 2021 Apr 16.

Abstract

In this case report, we describe the first case of Phialemonium obovatum infection involving the renal allograft in a recipient beyond 1 year after living renal transplant. The patient presented with a locally invasive mycetoma caused by this melanized fungus in the anterior abdominal wall, which extended during the hospital stay to involve the allograft. The fungus was identified by its characteristic micromorphological features present on potato dextrose agar and Sabourad dextrose agar and on subsequent slide cultures. The patient did not survive despite repeated surgical procedures, including partial allograft nephrectomy and broad-spectrum antifungal medications. Other cases of Phialemonium infections involving renal and stem cell transplant recipients are reviewed.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Agar
  • Allografts
  • Glucose
  • Humans
  • Kidney Transplantation* / adverse effects
  • Sordariales
  • Treatment Outcome

Substances

  • Agar
  • Glucose

Supplementary concepts

  • Phialemonium obovatum