Peripapillary Vessel Density in Eyes with Rhegmatogenous Retinal Detachment after Pars Plana Vitrectomy

Bing Lu; Pengfei Zhang; Haiyun Liu; Huixun Jia; Yang Yu; Fenghua Wang; Hong Wang; Xiaodong Sun

doi:10.1155/2021/6621820

Peripapillary Vessel Density in Eyes with Rhegmatogenous Retinal Detachment after Pars Plana Vitrectomy

J Ophthalmol. 2021 Mar 23:2021:6621820. doi: 10.1155/2021/6621820. eCollection 2021.

Authors

Bing Lu^{1

2

3}, Pengfei Zhang⁴, Haiyun Liu^{1

2

3

5}, Huixun Jia¹, Yang Yu¹, Fenghua Wang^{1

2

3

5

6}, Hong Wang^{1

2

3

5}, Xiaodong Sun^{1

2

3

5

6}

Affiliations

¹ Department of Ophthalmology, Shanghai General Hospital (Shanghai First People's Hospital), Shanghai Jiao Tong University School of Medicine, Shanghai, China.
² Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai, China.
³ National Clinical Research Center for Eye Diseases, Shanghai, China.
⁴ Department of Ophthalmology, The First Affiliated Hospital of Wannan Medical College, Wuhu, China.
⁵ Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases, Shanghai, China.
⁶ Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai, China.

Abstract

Purpose: To investigate the vascular density of the optic nerve head (ONH) and macula using optical coherence tomography angiography (OCTA) in patients undergoing vitrectomy for rhegmatogenous retinal detachment (RRD) and to evaluate associations with visual outcomes.

Methods: Patients with RRD, successfully treated with a pars plana vitrectomy (PPV) and a minimum three-month follow-up were included in this study. The vessel density (VD) of the ONH and peripapillary regions, foveal avascular zone (FAZ), foveal flow density (FFD), and parafoveal flow density (PFD) were evaluated using OCTA and compared to the fellow eye. Multivariate linear regression analysis was performed to determine correlations with visual outcomes.

Results: Thirty-one patients with macula-off RRD were included in the study. Compared with the fellow eyes, eyes after RRD surgery had a lower peripapillary VD (P < 0.01). No significant difference in superficial and deep FFD, PFD, and FAZ area was found compared to the fellow eyes. Postoperative peripapillary VD and baseline BCVA were significantly associated with BCVA three months after PPV (P < 0.05).

Conclusion: Rhegmatogenous retinal detachment eyes successfully treated with PPV had lower peripapillary vessel density than fellow healthy eyes. Postoperative BCVA was related to postoperative peripapillary VD.