Management of Severe and Refractory Ascites

Clin Liver Dis. 2021 May;25(2):431-440. doi: 10.1016/j.cld.2021.01.010. Epub 2021 Mar 11.

Abstract

Considering the poor prognosis, severe and refractory ascites is a milestone in cirrhotic patients. Liver transplantation must be considered first. In the case of contraindication to liver transplantation or when the waiting period is estimated to be more than 6 months, transjugular intrahepatic portosystemic shunt should be discussed in eligible patients. Regardless of the type of treatment, a careful selection of patients is crucial to avoid further decompensation and specific complications of each treatment.

Keywords: Albumin; Ascites; Cirrhosis; Large-volume paracentesis; Liver transplantation; Portal hypertension; TIPS.

Publication types

  • Review

MeSH terms

  • Ascites / etiology
  • Ascites / therapy
  • Humans
  • Liver Cirrhosis / complications
  • Liver Transplantation*
  • Portasystemic Shunt, Transjugular Intrahepatic*
  • Treatment Outcome