Patients with cardiac implantable electronic devices have usually been scheduled for routine in‑hospital visits. In addition, they are now monitored remotely. The remote monitoring of cardiac implantable electronic devices is a valuable tool to screen and triage patients at very high risk of deterioration. The continuous expansion of remote monitoring in real‑world settings brought a substantial increase of published evidence on the topic. Therefore, this review aims to summarize challenges and knowledge gaps in the field. Challenges that were identified as issues to be solved comprise warranty of data security and accessibility, integration with clinical repositories, patient selection and persistence, and resource availability. Future improvements of telemedicine will need to face these significant residual challenges.