Identifying and Understanding Transfusion Reactions in the Oncology Population

Semin Oncol Nurs. 2021 Apr;37(2):151137. doi: 10.1016/j.soncn.2021.151137. Epub 2021 Mar 19.

Abstract

Objectives: To provide an overview of transfusion reactions, their underlying pathophysiology, clinical presentation, and recommendations for nursing management.

Data sources: We researched peer-reviewed journal articles, book chapters, Internet, and lecture proceedings.

Conclusion: Transfusion reactions are adverse reactions to blood products frequently seen in the oncology population and can significantly vary in severity and etiology. Oncology nurses are in a critical position to assist with prevention, early detection, and time-sensitive treatment of transfusion reactions.

Implications for nursing practice: The oncology nurse's comprehensive understanding of possible transfusion reactions and management recommendations is key for optimal care of the oncology patient.

Keywords: Allergic transfusion reaction; Hemolytic transfusion reaction; Oncology nursing; Transfusion reaction; transfusion-associated circulatory overload; transfusion-related acute lung injury.

Publication types

  • Review

MeSH terms

  • Humans
  • Neoplasms* / therapy
  • Oncology Nursing
  • Transfusion Reaction*