Treatment of SCN4A-induced myotonic crisis

Muscle Nerve. 2021 Jun;63(6):E59-E61. doi: 10.1002/mus.27237. Epub 2021 Mar 31.
No abstract available

Keywords: SCN4A; malignant hyperthermia; myotonia; paramyotonia congenita.

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Dantrolene / therapeutic use*
  • Diazepam / therapeutic use*
  • Humans
  • Male
  • Muscle Relaxants, Central / therapeutic use*
  • Myotonia / drug therapy*
  • Myotonia / genetics
  • NAV1.4 Voltage-Gated Sodium Channel / genetics
  • Phenytoin / analogs & derivatives*
  • Phenytoin / therapeutic use
  • Sodium Channel Blockers / therapeutic use*
  • Young Adult

Substances

  • Muscle Relaxants, Central
  • NAV1.4 Voltage-Gated Sodium Channel
  • Sodium Channel Blockers
  • Phenytoin
  • fosphenytoin
  • Dantrolene
  • Diazepam

Supplementary concepts

  • Nondystrophic myotonia