First Report of a SARS-CoV-2 Genome Sequence with a Spike His69-Val70 Deletion and an Asn439Lys Mutation in Morocco

Tarik Aanniz; Mouna Ouadghiri; Mohammed Amine Bendahou; Mohammed Walid Chemao-Elfihri; Mohamed Chenaoui; Hanae Dakka; Afaf Allaoui; Otmane Touzani; Amina Benaouda; Bouchra Belefquih; Saaïd Amzazi; Lahcen Belyamani; Azeddine Ibrahimi

doi:10.1128/MRA.00027-21

First Report of a SARS-CoV-2 Genome Sequence with a Spike His69-Val70 Deletion and an Asn439Lys Mutation in Morocco

Microbiol Resour Announc. 2021 Mar 18;10(11):e00027-21. doi: 10.1128/MRA.00027-21.

Authors

Affiliations

¹ Medical Biotechnology Laboratory, Bioinova Research Center, Rabat Medical and Pharmacy School, Mohammed Vth University, Rabat, Morocco.
² Research Center of Plant and Microbial Biotechnologies, Biodiversity, and Environment, Faculty of Sciences, Mohammed Vth University, Rabat, Morocco.
³ Laboratoire d'Analyse Médicales Biolife, Harhoura, Temara, Morocco.
⁴ Laboratoire de Biologie des Pathologies Humaines, Faculté des Sciences, Mohammed Vth University, Rabat, Morocco.
⁵ Laboratoire de Biodiversité, Écologie, et Génome, Faculté des Sciences, Mohammed Vth University, Rabat, Morocco.
⁶ Laboratoire Touzani d'Analyses Biologiques et Médicales, Temara, Morocco.
⁷ Microbiology Laboratory, Cheikh-Zaid University Hospital, Abulcasis University of Health Sciences, Rabat, Morocco.
⁸ Laboratory of Human Pathologies Biology, Faculty of Sciences, Mohammed Vth University, Rabat, Morocco.
⁹ Emergency Department, Military Hospital Mohammed V, Rabat Medical and Pharmacy School, Mohammed Vth University, Rabat, Morocco.
¹⁰ Medical Biotechnology Laboratory, Bioinova Research Center, Rabat Medical and Pharmacy School, Mohammed Vth University, Rabat, Morocco a.ibrahimi@um5s.net.ma.

Abstract

We report the nearly complete genome sequence and the genetic variations of a clinical sample of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) collected from a nasopharyngeal swab specimen from a male patient from Harhoura-Rabat, Morocco. The sequence, which was obtained using Ion Torrent technology, is valuable as it carries a recently described deletion (His69-Val70) and substitution (Asn439Lys).