Characteristics of Patients Undergoing Endoscopic Retrograde Cholangiopancreatography for Sphincter of Oddi Disorders

Gregory A Coté; Haley Nitchie; B Joseph Elmunzer; Richard S Kwon; Field F Willingham; Sachin Wani; Daniel Mullady; Amitabh Chak; Vikesh Singh; Adam Slivka; Shyam Varadarajulu; Martin Freeman; Srinivas Gaddam; Priya Jamidar; Paul Tarnasky; Lydia Foster; Peter B Cotton

doi:10.1016/j.cgh.2021.03.008

Characteristics of Patients Undergoing Endoscopic Retrograde Cholangiopancreatography for Sphincter of Oddi Disorders

Clin Gastroenterol Hepatol. 2022 Mar;20(3):e627-e634. doi: 10.1016/j.cgh.2021.03.008. Epub 2021 Mar 11.

Authors

Gregory A Coté¹, Haley Nitchie², B Joseph Elmunzer², Richard S Kwon³, Field F Willingham⁴, Sachin Wani⁵, Daniel Mullady⁶, Amitabh Chak⁷, Vikesh Singh⁸, Adam Slivka⁹, Shyam Varadarajulu¹⁰, Martin Freeman¹¹, Srinivas Gaddam¹², Priya Jamidar¹³, Paul Tarnasky¹⁴, Lydia Foster¹⁵, Peter B Cotton²

Affiliations

¹ Division of Gastroenterology and Hepatology, Department of Medicine, Charleston, South Carolina. Electronic address: cotea@musc.edu.
² Division of Gastroenterology and Hepatology, Department of Medicine, Charleston, South Carolina.
³ Division of Gastroenterology and Hepatology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan.
⁴ Division of Digestive Diseases, Department of Medicine, School of Medicine, Emory University, Atlanta, Georgia.
⁵ Division of Gastroenterology and Hepatology, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado.
⁶ Division of Gastroenterology, Department of Medicine, Washington University in St. Louis School of Medicine, St. Louis, Missouri.
⁷ Department of Medicine, Case Western Reserve University, Cleveland, Ohio.
⁸ Division of Gastroenterology, Johns Hopkins Medical Institutions, Baltimore, Maryland.
⁹ Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania.
¹⁰ Advent Health, Orlando, Florida.
¹¹ Department of Medicine, University of Minnesota, Minneapolis, Minnesota.
¹² Department of Medicine, Cedars Sinai School of Medicine, Los Angeles, California.
¹³ Department of Medicine, Yale University School of Medicine, New Haven, Connecticut.
¹⁴ Methodist Digestive Institute, Dallas, Texas.
¹⁵ Department of Public Health, Medical University of South Carolina, Charleston, South Carolina.

Abstract

The concept that sphincter of Oddi dysfunction (SOD) can cause attacks of biliary-type pain in postcholecystectomy patients and those with unexplained recurrent acute pancreatitis, and that endoscopic sphincterotomy can ameliorate symptoms, remains unproven. The Evaluating Predictors and Interventions in Sphincter of Oddi Dysfunction (EPISOD) study of patients without objective evidence for biliary obstruction showed no difference in outcomes between those who underwent sphincterotomy or sham treatment.¹ To date, there have been no studies examining the characteristics of patients who still are being offered endoscopic retrograde cholangiopancreatography (ERCP) for SOD since the EPISOD publication, although the absolute number appears to have declined.².

Keywords: ERCP; Functional GI Disorders; Sphincter of Oddi Dysfunction; Sphincterotomy.

Publication types

Research Support, N.I.H., Extramural

MeSH terms

Acute Disease
Cholangiopancreatography, Endoscopic Retrograde / adverse effects
Humans
Manometry
Pancreatitis* / diagnosis
Pancreatitis* / etiology
Pancreatitis* / surgery
Sphincter of Oddi* / surgery
Sphincterotomy, Endoscopic

Abstract

Publication types

MeSH terms

Grants and funding