Clostridioides difficile infection: a comprehensive review for primary providers

Rom J Intern Med. 2021 Aug 26;59(3):262-269. doi: 10.2478/rjim-2021-0010. Print 2021 Sep 1.

Abstract

Clostridioides difficile infection (CDI) is an issue of great concern due to its rising incidence, recurrence, morbidity and impact on healthcare spending. Treatment guidelines have changed in the last few years, and new therapies are being considered. This is a practical review for the primary care practitioner of the latest guidelines for CDI diagnosis, treatment, and emerging therapies.

Keywords: Clostridioides difficile; eradication; fecal microbiota transplantation; recurrent infection.

Publication types

  • Review

MeSH terms

  • Clostridioides difficile / isolation & purification*
  • Clostridium Infections* / diagnosis
  • Clostridium Infections* / epidemiology
  • Clostridium Infections* / therapy
  • Fecal Microbiota Transplantation*
  • Humans
  • Recurrence
  • Treatment Outcome