Short-Chain Enoyl-CoA Hydratase Mediates Histone Crotonylation and Contributes to Cardiac Homeostasis

Circulation. 2021 Mar 9;143(10):1066-1069. doi: 10.1161/CIRCULATIONAHA.120.049438. Epub 2021 Mar 8.

Authors

Xiaoqiang Tang^#¹, Xiao-Feng Chen^#¹, Xin Sun^#¹, Peng Xu¹, Xiang Zhao¹, Ying Tong¹, Xiao-Man Wang¹, Ke Yang¹, Yu-Tong Zhu¹, De-Long Hao¹, Zhu-Qin Zhang¹, De-Pei Liu¹, Hou-Zao Chen¹

Affiliation

¹ Department of Biochemistry and Molecular Biology, State Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

^# Contributed equally.

PMID: 33683949
DOI: 10.1161/CIRCULATIONAHA.120.049438

No abstract available

Keywords: cardiomegaly; enoyl-CoA hydratase; histones; transcription factors.

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Cardiovascular Diseases / genetics*
Enoyl-CoA Hydratase / metabolism*
Histones / metabolism*
Homeostasis / physiology*
Humans

Substances

Histones
Enoyl-CoA Hydratase