Comparative pharmacokinetic analysis of the blood-brain barrier penetration of dasatinib and ponatinib in mice

Leuk Lymphoma. 2021 Aug;62(8):1990-1994. doi: 10.1080/10428194.2021.1894647. Epub 2021 Mar 7.

Authors

Affiliations

¹ Department of Pediatrics, University of Michigan Medical School, Ann Arbor, MI, USA.
² University of Michigan College of Pharmacy, Ann Arbor, MI, USA.
³ Medical College of Wisconsin, Wauwatosa, WI, USA.
⁴ Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI, USA.

No abstract available

Publication types

Letter
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

MeSH terms

Animals
Blood-Brain Barrier*
Dasatinib
Imidazoles
Mice
Protein Kinase Inhibitors
Pyridazines*

Substances

Imidazoles
Protein Kinase Inhibitors
Pyridazines
ponatinib
Dasatinib

Grants and funding

P30 CA046592/CA/NCI NIH HHS/United States