Drug Distribution

Excerpt

Pharmacokinetics is the study of a drug moiety or a compound as it moves through the body after its administration. It involves the processes of drug absorption, bioavailability, clearance, and distribution. Although these processes are theoretically separate, from a practical standpoint in-vivo, they are all inter-connected. After the drug is absorbed from the site of administration, it is distributed to extracellular fluids. High reserves of plasma protein-bound drugs can cause prolonged effects by creating a sustained release mechanism.