Uncertainty remains about how long the protective immune responses against severe acute respiratory syndrome coronavirus 2 persists, and suspected reinfection in recovered patients has been reported. We describe a case of reinfection from distinct virus lineages in Brazil harboring the E484K mutation, a variant associated with escape from neutralizing antibodies.
Keywords: Brazil; COVID-19; E484K spike mutation; SARS-CoV-2; coronavirus disease; genomic surveillance; reinfection; respiratory infections; severe acute respiratory syndrome coronavirus 2; viruses; zoonoses.