British Association of Dermatologists National Clinical Audit on the Management of Hidradenitis Suppurativa in the UK

Clin Exp Dermatol. 2021 Aug;46(6):1023-1027. doi: 10.1111/ced.14598. Epub 2021 Mar 18.

Abstract

Background: The first UK guidelines for the management of hidradenitis suppurativa (HS) were published by the British Association of Dermatologists (BAD) in 2018. The guidelines contained a set of audit criteria.

Aim: To evaluate current HS management against the audit standards in the BAD guidelines.

Methods: BAD members were invited to complete audit questionnaires between January and May 2020 for five consecutive patients with HS per department.

Results: In total, 88 centres participated, providing data for 406 patients. Disease staging using the Hurley system and disease severity using a validated tool during follow-ups was documented in 75% and 56% of cases, respectively, while quality of life and pain were documented in 49% and 50% of cases, respectively. Screening for cardiovascular disease risk factors was as follows: smoking 75%, body mass index 27% and others such as lipids and diabetes 57%. Screening for depression and anxiety was performed in 40% and 25% of cases, respectively. Support for smokers or obese patients was documented in 35% and 23% of cases. In total, 182 patients were on adalimumab, of whom 68% had documentation of baseline disease severity, and 76% were reported as having inadequate response or contraindications to systemic treatments; 44% of patients continued on adalimumab despite having < 25% improvement in lesion count.

Conclusion: UK dermatologists performed well against several audit standards, including documenting disease staging at baseline and smoking status. However, improvements are needed, particularly with regard to screening and management of comorbidities that could reduce the long-term complications associated with HS. A re-audit is required to evaluate changes in practice in the future.

MeSH terms

  • Adalimumab / therapeutic use
  • Anti-Infective Agents, Local / therapeutic use
  • Anti-Inflammatory Agents / therapeutic use
  • Body Mass Index
  • Clinical Audit*
  • Dermatologic Agents / therapeutic use
  • Guideline Adherence
  • Hidradenitis Suppurativa / complications
  • Hidradenitis Suppurativa / diagnosis*
  • Hidradenitis Suppurativa / drug therapy*
  • Humans
  • Practice Guidelines as Topic
  • Quality of Life
  • Risk Factors
  • Severity of Illness Index
  • Smoking / adverse effects
  • Tetracyclines / therapeutic use
  • United Kingdom

Substances

  • Anti-Infective Agents, Local
  • Anti-Inflammatory Agents
  • Dermatologic Agents
  • Tetracyclines
  • Adalimumab