Spontaneous unscarred uterine rupture in a twin pregnancy complicated by adenomyosis: A case report

Medicine (Baltimore). 2021 Jan 22;100(3):e24048. doi: 10.1097/MD.0000000000024048.

Abstract

Introduction: Uterine rupture during pregnancy is a serious obstetric complication accompanied by a high incidence of maternal morbidity and mortality, and the presence of uterine scars is the main risk factor. In the present case, uterine rupture occurred in an unscarred uterus in a nonlaboring primigravida woman with adenomyosis and twin pregnancy in the third trimester.

Patient concerns: In this case, the patient suspected to have a history of endometriosis have got twin pregnancies following intracytoplasmic sperm injection, and complained of recurrent lower abdominal pain from 16 weeks to 29 weeks of gestation.

Diagnosis: After exploratory laparotomy, the patient was diagnosed with uterine rupture and adenomyosis.

Interventions: The patient was first administered expectant treatment such as antibiotics, tocolytics, and fluid replacement therapy. Symptoms then appeared repeatedly and worsened, followed by eventual peritoneal irritation, and exploratory laparotomy was performed.

Outcomes: Two live female fetuses were extracted by cesarean section, and the uterine laceration was repaired. The mother recovered without any postoperative complications, and the babies were discharged after receiving one month of prematurity care without any postnatal complications.

Conclusion: Adenomyosis and the conception of twins may lead to uterine rupture. For pregnant women with a history of adenomyosis with multiple gestations, close monitoring for signs of uterine rupture is necessary. Single-embryo transfer and multifetal pregnancy reduction should be recommended for infertile patients with adenomyosis.

Publication types

  • Case Reports

MeSH terms

  • Adenomyosis / complications*
  • Adult
  • Cesarean Section
  • Female
  • Humans
  • Live Birth
  • Pregnancy
  • Pregnancy Complications / etiology*
  • Pregnancy Trimester, Third
  • Pregnancy, Twin*
  • Premature Birth / etiology*
  • Rupture, Spontaneous
  • Uterine Rupture / etiology*