First Reported Case of Hyperchloremic Non-Anion Gap Metabolic Acidosis in a Patient Undergoing Continuous Bladder Irrigation for Hemorrhagic Cystitis

Azka Latif; Joseph Thirumalareddy; Akshat Sood; Sunil Nair; Abubakar Tauseef

doi:10.7759/cureus.12132

First Reported Case of Hyperchloremic Non-Anion Gap Metabolic Acidosis in a Patient Undergoing Continuous Bladder Irrigation for Hemorrhagic Cystitis

Cureus. 2020 Dec 17;12(12):e12132. doi: 10.7759/cureus.12132.

Authors

Azka Latif¹, Joseph Thirumalareddy², Akshat Sood¹, Sunil Nair³, Abubakar Tauseef⁴

Affiliations

¹ Internal Medicine, CHI Creighton University, Omaha, USA.
² Hospital Medicine, Creighton University School of Medicine, St. Joseph's Hospital and Medical Center, Omaha, USA.
³ Internal Medicine, Creighton University School of Medicine, Omaha, USA.
⁴ Internal Medicine, Creighton University, Omaha, USA.

Abstract

Radiation cystitis can present as gross hematuria and occurs secondary to irritation of the bladder urothelium. Continuous bladder irrigation (CBI) is commonly used for the treatment of hemorrhagic cystitis for evacuation of blood clots and to maintain catheter drainage. Most commonly, CBI is performed using 0.9% sodium chloride. We report a 77-year-old female who developed hyperchloremic non-anion gap metabolic acidosis (H-NAGMA) and pulmonary edema secondary to absorption of 0.9% normal saline (NS) from CBI. In such cases, ringer lactate with low concentration (109 mEq) of chloride as compared to NS (154 mEq) can prove to be a suitable alternative.

Keywords: bladder irrigation; cystitis; hyperchloremic; non-anion gap metabolic acidosis; undergoing.

Publication types

Case Reports