ABO blood groups and risk of covid-19

Tunis Med. 2020 Dec;98(12):888-891.

Abstract

Introduction: Coronavirus pandemic has been the subject of a large number of publications, some of which have shown an increased risk of contracting Covid-19 in carriers of blood group A.

Aims: In this study we looked at the profile of blood group phenotype of a series of Tunisian patients with covid-19 admitted to Abderrahman Mami hospital in Ariana .

Methods: Our study included 51 Tunisian patients with SARS-CoV-2 infection admitted to Abderrahmane Mami hospital between late march 2020 and early May 2020. The distribution of blood groups in Covid-19 patients was compared with that of a control group of 1506 patients with no Covid-19 infection as well as with the distribution of blood groups in a population of 63375 voluntary blood donors.

Results: Our series, although limited in size, showed a higher prevalence of blood group A among Covid-19 patients, statistically significant compared to ABO blood group distribution among Tunisian blood donors and among a control group of patients without Covid -19.

Conclusion: these results are in line with data from the literature, particularly on larger series in China.

MeSH terms

  • ABO Blood-Group System / adverse effects
  • ABO Blood-Group System / blood
  • ABO Blood-Group System / physiology*
  • Adult
  • Aged
  • Aged, 80 and over
  • Blood Donors / statistics & numerical data
  • COVID-19 / blood
  • COVID-19 / epidemiology*
  • COVID-19 / etiology*
  • COVID-19 / therapy
  • Case-Control Studies
  • Disease Susceptibility / blood
  • Disease Susceptibility / epidemiology
  • Female
  • Hospitalization / statistics & numerical data
  • Humans
  • Male
  • Middle Aged
  • Pandemics
  • Risk Factors
  • SARS-CoV-2 / physiology
  • Tunisia / epidemiology

Substances

  • ABO Blood-Group System