The impact of late-treated pediatric cataract on intraocular pressure

Int Ophthalmol. 2021 Apr;41(4):1531-1539. doi: 10.1007/s10792-021-01727-y. Epub 2021 Jan 20.

Abstract

Purpose: To assess the intraocular pressure and visual acuity before and after pediatric congenital cataract surgery performed at a relatively older age.

Methods: A retrospective analysis of all consecutive pediatric patients diagnosed and operated for bilateral congenital cataracts during a seven-year period (2012-2018) in rural southern Ethiopia. Non-ambulatory vision was defined as hand motion or worse. The main outcome measures were intraocular pressure (IOP) and visual acuity.

Results: Thirty-two children were included, 17 females (53.1%), with a mean age of 11 years (± 2.83) [range, 7-18]. A total of 59 eyes were operated on. The mean follow-up was 4.8 ± 1.8 years (range, 2-8). VA improved from 20/1400 preoperatively to 20/440 postoperatively OD and 20/540 OS (p < 0.001). More eyes had ambulatory vision after cataract surgery than pre-surgery (56 eyes [95%] vs. 29 eyes [49%], p < 0.001). The IOP decreased from a mean preoperative value of 18.4 ± 7.1 mmHg to 14.5 ± 2.9 postoperatively OD (p < 0.001) and 16.3 ± 5.9 mmHg to 13.9 ± 3.5 OS (p < 0.001). Fifteen eyes (24%) had increased IOP (> 21 mmHg) preoperatively, of which three remained high after surgery. Positive correlations were found between IOP, axial length and cup-to-disc ratio. None of the patients required pressure-lowering procedures.

Conclusion: Bilateral congenital cataracts may be associated with ocular hypertension, with possible progression to glaucoma if left untreated. Surgery at a relatively older age often was associated with a significant improvement in intraocular pressure and ambulatory vision.

Keywords: Congenital cataract; Pediatric glaucoma following cataract surgery; Pseudophakic glaucoma.

MeSH terms

  • Aged
  • Cataract Extraction*
  • Cataract* / epidemiology
  • Child
  • Female
  • Follow-Up Studies
  • Glaucoma* / epidemiology
  • Glaucoma* / etiology
  • Glaucoma* / surgery
  • Humans
  • Intraocular Pressure
  • Retrospective Studies
  • Tonometry, Ocular
  • Treatment Outcome