Inhibition of ULK1 promotes the death of leukemia cell in an autophagy irrelevant manner and exerts the antileukemia effect

Clin Transl Med. 2021 Jan;11(1):e282. doi: 10.1002/ctm2.282.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Antineoplastic Agents / pharmacology*
  • Autophagy / drug effects
  • Autophagy / genetics*
  • Autophagy-Related Protein-1 Homolog / antagonists & inhibitors*
  • Autophagy-Related Protein-1 Homolog / genetics*
  • Databases, Factual
  • Disease Models, Animal
  • Humans
  • Intracellular Signaling Peptides and Proteins / antagonists & inhibitors*
  • Intracellular Signaling Peptides and Proteins / genetics*
  • Leukemia, Myeloid, Acute / drug therapy*
  • Leukemia, Myeloid, Acute / genetics*
  • Leukemia, Myeloid, Acute / pathology
  • Mice

Substances

  • Antineoplastic Agents
  • Intracellular Signaling Peptides and Proteins
  • Autophagy-Related Protein-1 Homolog
  • ULK1 protein, human