Prosthetic Valve Endocarditis Diagnosis and Management- New Paradigm Shift Narratives

Arnold S Bayer; Henry F Chambers

doi:10.1093/cid/ciab036

Prosthetic Valve Endocarditis Diagnosis and Management- New Paradigm Shift Narratives

Clin Infect Dis. 2021 May 18;72(10):1687-1692. doi: 10.1093/cid/ciab036.

Authors

Arnold S Bayer^{1

2}, Henry F Chambers³

Affiliations

¹ The Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, California, USA.
² The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, California, USA.
³ The Department of Medicine, Division of HIV, Infectious Diseases and Global Medicine, Zuckerberg San Francisco General Hospital, University of California, San Francisco School of Medicine, San Francisco, California, USA.

PMID: 33458755
DOI: 10.1093/cid/ciab036

Abstract

Prosthetic valve endocarditis (PVE) is a major infectious disease problem due to the increasing numbers of patients undergoing valve replacement surgery. PVE can present diagnostic difficulties echocardiographically, especially when complicating transvascular placement techniques. Moreover, outbreaks of unusual PVE pathogens, such as Mycobacterium chimaera, have presented major diagnostic and therapeutic dilemmas.

Keywords: Mycobacterium chimaera; PET-CT; endocarditis; prosthetic valves.

MeSH terms

Endocarditis* / diagnosis
Endocarditis, Bacterial* / diagnosis
Endocarditis, Bacterial* / drug therapy
Heart Valve Prosthesis* / adverse effects
Humans
Mycobacterium
Prosthesis-Related Infections* / diagnosis
Prosthesis-Related Infections* / therapy

Supplementary concepts

Mycobacterium chimaera