Disseminated Legionella micdadei infection in a liver transplant patient presenting as pulmonary nodules and a laryngeal lesion

Allison R Bond; Emma Bainbridge; Sarah B Doernberg; Jennifer M Babik; Steve Miller; Elham Khanafshar; Travis Henry; Abel David; Matthew Russell; Danielle Brandman; Courtney B Sherman; Francis Yao; Monica Fung

doi:10.1111/tid.13563

Disseminated Legionella micdadei infection in a liver transplant patient presenting as pulmonary nodules and a laryngeal lesion

Transpl Infect Dis. 2021 Jun;23(3):e13563. doi: 10.1111/tid.13563. Epub 2021 Feb 18.

Authors

Affiliations

¹ Division of Infectious Disease, Department of Medicine, University of California San Francisco, San Francisco, CA, USA.
² Department of Laboratory Medicine, University of California San Francisco, San Francisco, CA, USA.
³ Department of Pathology, University of California San Francisco, San Francisco, CA, USA.
⁴ Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA, USA.
⁵ Department of Otolaryngology-Head and Neck Surgery, University of California San Francisco, San Francisco, CA, USA.
⁶ Division of Gastroenterology, Department of Medicine, University of California San Francisco, San Francisco, CA, USA.

PMID: 33434394
DOI: 10.1111/tid.13563

Abstract

We report a liver transplant patient with disseminated Legionella micdadei infection with pulmonary, laryngeal, and suspected muscle involvement. This organism, which stains weakly acid-fast, primarily affects immunocompromised patients. The diagnosis is difficult to make; in this case, the organism was identified via molecular diagnostics on laryngeal and pulmonary biopsy tissue.

Keywords: Legionella micdadei; liver transplant; molecular diagnostics; pulmonary nodules.

Publication types

Case Reports

MeSH terms

Humans
Legionella*
Legionellaceae
Legionellosis*
Liver Transplantation*
Lung

Supplementary concepts

Tatlockia micdadei