Cloning and sequencing of cDNA that encodes goat growth hormone

FEBS Lett. 1988 Feb 15;228(2):301-4. doi: 10.1016/0014-5793(88)80020-6.

Abstract

The cDNA that encodes goat growth hormone (gGH) was isolated from a goat pituitary cDNA library. The cDNA, about 880 base pairs long, had a coding sequence, 5'- and 3'-untranslated regions and a poly(A) chain. The cDNA could encode a polypeptide of 217 amino acids. The amino acid sequence homology between gGH and the sequences of bovine GH, rat GH and human GH was 99, 83 and 66%, respectively. By Northern blot hybridization, we found that the possible gGH gene is transcribed in the goat pituitary.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Base Sequence
  • Cloning, Molecular*
  • DNA / genetics*
  • DNA, Recombinant
  • Goats / genetics*
  • Growth Hormone / genetics*
  • Molecular Sequence Data
  • Nucleic Acid Hybridization
  • Pituitary Gland / analysis
  • RNA, Messenger / genetics
  • Sequence Homology, Nucleic Acid

Substances

  • DNA, Recombinant
  • RNA, Messenger
  • Growth Hormone
  • DNA

Associated data

  • GENBANK/Y00767