USP20 links feeding-induced cholesterol synthesis and energy expenditure

Sci China Life Sci. 2021 Feb;64(2):337-338. doi: 10.1007/s11427-020-1867-8. Epub 2021 Jan 6.

Authors

Xu Xiao¹, Peter Tontonoz²

Affiliations

¹ Department of Pathology and Laboratory Medicine and Department of Biological Chemistry, University of California, Los Angeles, CA, 90095, USA.
² Department of Pathology and Laboratory Medicine and Department of Biological Chemistry, University of California, Los Angeles, CA, 90095, USA. ptontonoz@mednet.ucla.edu.

PMID: 33420925
DOI: 10.1007/s11427-020-1867-8

No abstract available

MeSH terms

Animals
Cholesterol / biosynthesis*
Eating / physiology*
Energy Metabolism / genetics
Energy Metabolism / physiology*
Humans
Hydroxymethylglutaryl CoA Reductases / metabolism
Metabolic Diseases / genetics
Metabolic Diseases / metabolism
Mice
Mice, Knockout
Models, Biological
Ubiquitin Thiolesterase / antagonists & inhibitors
Ubiquitin Thiolesterase / genetics
Ubiquitin Thiolesterase / metabolism*

Substances

Cholesterol
Hydroxymethylglutaryl CoA Reductases
Ubiquitin Thiolesterase
Usp20 protein, mouse