Central line-related bloodstream infections and microbiological study in an Egyptian Ministry of Health Hospital

Afr Health Sci. 2020 Mar;20(1):158-167. doi: 10.4314/ahs.v20i1.21.

Abstract

Background: Central line-associated bloodstream infections continue to be one of the most important health problems in ICU.

Objectives: To identify the central line-related bloodstream infections and their microbiological characteristics Specific objectives to the identify the incidence, predisposing factors of central line-related bloodstream Infections and study the antibiotic sensitivity patterns of the isolated organisms.

Material and methods: Patients' demographic, clinical data, central venous catheter related data,and blood culture specimen collection data were collected utilizing a descriptive exploratory design from a purposive sample of 120 ICU patients underwent insertion central venous catheter.

Results: out of 120 central line catheters sent for culture from patients immediately and seven days after insertion., 13(10.83%) were positive seven days after insertion. Of the 13 infection cases, 10 cases were Staphylococcus epidermis and the others were Staphylococcus aureus. In addition, most infected patients were overweight and obese, diabetic, had sub-clavian route, and their length of hospital stayed more than7 days.

Conclusion: 10.83 % developed bacterial blood stream infection 7 days after insertion of central venous catheters, and most of bacterial isolates were Staphylococcus epidermis and were sensitive to Vancomycin and Amikain.

Keywords: Antibiotic Resistance; Bacterial Infections; Bacterial Isolates.

MeSH terms

  • Adult
  • Aged
  • Anti-Bacterial Agents / therapeutic use
  • Bacteremia / epidemiology
  • Bacteremia / microbiology*
  • Bacterial Infections / drug therapy
  • Bacterial Infections / epidemiology
  • Catheterization, Central Venous / adverse effects*
  • Central Venous Catheters / adverse effects
  • Central Venous Catheters / microbiology*
  • Comorbidity
  • Cross Infection / drug therapy
  • Cross Infection / microbiology*
  • Diabetes Mellitus, Type 2 / epidemiology
  • Drug Resistance, Microbial
  • Egypt
  • Female
  • Humans
  • Incidence
  • Length of Stay
  • Male
  • Middle Aged
  • Obesity / epidemiology
  • Staphylococcal Infections / drug therapy
  • Staphylococcus aureus / isolation & purification
  • Staphylococcus epidermidis / isolation & purification

Substances

  • Anti-Bacterial Agents