A mouse model for SARS-CoV-2-induced acute respiratory distress syndrome

Weiqi Hong; Jingyun Yang; Zhenfei Bi; Cai He; Hong Lei; Wenhai Yu; Yun Yang; Changfa Fan; Shuaiyao Lu; Xiaozhong Peng; Xiawei Wei

doi:10.1038/s41392-020-00451-w

A mouse model for SARS-CoV-2-induced acute respiratory distress syndrome

Signal Transduct Target Ther. 2021 Jan 1;6(1):1. doi: 10.1038/s41392-020-00451-w.

Authors

Weiqi Hong¹, Jingyun Yang¹, Zhenfei Bi¹, Cai He¹, Hong Lei¹, Wenhai Yu², Yun Yang², Changfa Fan³, Shuaiyao Lu⁴, Xiaozhong Peng^{5

6}, Xiawei Wei⁷

Affiliations

¹ Laboratory of Aging Research and Cancer Drug Target, State Key Laboratory of Biotherapy and Cancer Center, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, No. 17, Block 3, Southern Renmin Road, 610041, Chengdu, Sichuan, People's Republic of China.
² National Kunming High-level Biosafety Primate Research Center, Institute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Yunnan, China.
³ Division of Animal Model Research, Institute for Laboratory Animal Resources, National Institutes for Food and Drug Control, 102629, Beijing, China.
⁴ National Kunming High-level Biosafety Primate Research Center, Institute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Yunnan, China. lushuaiyao-km@163.com.
⁵ National Kunming High-level Biosafety Primate Research Center, Institute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Yunnan, China. pengxiaozhong@pumc.edu.cn.
⁶ State Key Laboratory of Medical Molecular Biology, Department of Molecular Biology and Biochemistry, Institute of Basic Medical Sciences, Medical Primate Research Center, Neuroscience Center, Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, Beijing, China. pengxiaozhong@pumc.edu.cn.
⁷ Laboratory of Aging Research and Cancer Drug Target, State Key Laboratory of Biotherapy and Cancer Center, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, No. 17, Block 3, Southern Renmin Road, 610041, Chengdu, Sichuan, People's Republic of China. xiaweiwei@scu.edu.cn.

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Animals
COVID-19* / genetics
COVID-19* / metabolism
COVID-19* / pathology
Disease Models, Animal*
Humans
Mice
Mice, Transgenic
Respiratory Distress Syndrome* / genetics
Respiratory Distress Syndrome* / metabolism
Respiratory Distress Syndrome* / pathology
Respiratory Distress Syndrome* / virology
SARS-CoV-2* / genetics
SARS-CoV-2* / metabolism