Fundus Pigmentation in the Diagnosis and Treatment of Retinopathy of Prematurity

Ophthalmology. 2021 Aug;128(8):1242-1244. doi: 10.1016/j.ophtha.2020.12.024. Epub 2020 Dec 29.

Abstract

1,259 premature infants at risk for ROP were evaluated. 29% were diagnosed with ROP and 39.4% had light fundus pigmentation (FP). Light FP had a higher association with ROP diagnosis and higher risk ROP features.

Keywords: Fundus pigmentation; Intravitreal bevacizumab; Pediatric retina; Retinopathy of prematurity.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Angiogenesis Inhibitors / therapeutic use*
  • Bevacizumab / therapeutic use*
  • Birth Weight
  • Female
  • Fundus Oculi*
  • Gestational Age
  • Humans
  • Infant, Newborn
  • Intravitreal Injections
  • Male
  • Pigmentation / physiology*
  • Retinopathy of Prematurity / diagnosis*
  • Retinopathy of Prematurity / drug therapy*
  • Retrospective Studies
  • Vascular Endothelial Growth Factor A / antagonists & inhibitors

Substances

  • Angiogenesis Inhibitors
  • VEGFA protein, human
  • Vascular Endothelial Growth Factor A
  • Bevacizumab