Green Process for 5-(Chloromethyl)furfural Production from Biomass in Three-Constituent Deep Eutectic Solvent

Binglin Chen; Zheng Li; Yunchao Feng; Weiwei Hao; Yong Sun; Xing Tang; Xianhai Zeng; Lu Lin

doi:10.1002/cssc.202002631

Green Process for 5-(Chloromethyl)furfural Production from Biomass in Three-Constituent Deep Eutectic Solvent

ChemSusChem. 2021 Feb 5;14(3):847-851. doi: 10.1002/cssc.202002631. Epub 2021 Jan 5.

Authors

Binglin Chen¹, Zheng Li², Yunchao Feng¹, Weiwei Hao¹, Yong Sun^{1

3

4}, Xing Tang^{1

3

4}, Xianhai Zeng^{1

3

4}, Lu Lin^{1

3

4}

Affiliations

¹ College of Energy, Xiamen University, Xiamen, 361102, P.R. China.
² Department of Biological Systems Engineering, University of Wisconsin, Madison, 53719, USA.
³ Fujian Engineering and Research Centre of Clean and High-valued Technologies for Biomass, Xiamen, 361102, P. R. China.
⁴ Xiamen Key Laboratory of Clean and High-valued Utilization for Biomass, Xiamen, 361102, P. R. China.

PMID: 33347742
DOI: 10.1002/cssc.202002631

Abstract

5-(Chloromethyl)furfural (CMF), a versatile bio-platform molecule, was first synthesized in a three-constituent deep eutectic solvent (3c-DES) including choline chloride, AlCl₃ ⋅ 6H₂ O, and oxalic acid. In particular, 3c-DES was conducive for the production of CMF from glucose and provided a CMF yield of 70 % at 120 °C within 30 min. In addition, CMF yields reached up to 86, 80, 30, 29, and 35 % from fructose, sucrose, cellulose, bamboo, and bamboo pulp, respectively. This study opens new avenues for the preparation of CMF.

Keywords: 5-(chloromethyl)furfural (CMF); Carbohydrates; biomass; deep eutectic solvent; green chemistry.

Abstract

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