Treatment of Mobile Right Heart Thrombi

Eur J Case Rep Intern Med. 2020 Sep 17;7(12):001918. doi: 10.12890/2020_001918. eCollection 2020.

Abstract

Right heart thrombi are detected in approximately 4% of patients with pulmonary embolism. The associated mortality is high, but the optimal strategy remains controversial. We report a case of a large mobile right heart thrombus, complicated by embolism of the right pulmonary artery, which was successfully treated with half-dose alteplase. We briefly review the literature and discuss the therapeutic options, focusing on the advantages of thrombolysis.

Learning points: Mobile right heart thrombi require rapid therapeutic choices between surgical thrombectomy and thrombolysis.Half-dose alteplase may be effective, even in the presence of an extensive thrombus burden.

Keywords: Mobile right heart thrombi; half-dose alteplase; pulmonary embolism.