AsthmaMap: An interactive knowledge repository for mechanisms of asthma

Alexander Mazein; Olga Ivanova; Irina Balaur; Marek Ostaszewski; Valeriya Berzhitskaya; Tatiana Serebriyskaya; Thomas Ligon; Jan Hasenauer; Bertrand De Meulder; Rupert W Overall; Ludovic Roy; Richard G Knowles; Craig E Wheelock; Sven-Erik Dahlen; Kian Fan Chung; Ian M Adcock; Graham Roberts; Ratko Djukanovic; Johann Pellet; Piotr Gawron; Rudi Balling; Anke H Maitland-van der Zee; Reinhard Schneider; Peter J Sterk; Charles Auffray; U-BIOPRED Study Group,; eTRIKS Consortium

doi:10.1016/j.jaci.2020.11.032

AsthmaMap: An interactive knowledge repository for mechanisms of asthma

J Allergy Clin Immunol. 2021 Mar;147(3):853-856. doi: 10.1016/j.jaci.2020.11.032. Epub 2020 Dec 9.

Authors

Alexander Mazein¹, Olga Ivanova², Irina Balaur³, Marek Ostaszewski⁴, Valeriya Berzhitskaya⁵, Tatiana Serebriyskaya⁵, Thomas Ligon⁶, Jan Hasenauer⁷, Bertrand De Meulder³, Rupert W Overall⁸, Ludovic Roy³, Richard G Knowles⁹, Craig E Wheelock¹⁰, Sven-Erik Dahlen¹¹, Kian Fan Chung¹², Ian M Adcock¹², Graham Roberts¹³, Ratko Djukanovic¹⁴, Johann Pellet³, Piotr Gawron⁴, Rudi Balling⁴, Anke H Maitland-van der Zee¹⁵, Reinhard Schneider⁴, Peter J Sterk¹⁵, Charles Auffray³; U-BIOPRED Study Group,; eTRIKS Consortium

Affiliations

¹ European Institute for Systems Biology and Medicine, Université de Lyon, Lyon, France; Institute of Cell Biophysics, Russian Academy of Sciences, Pushchino, Moscow, Russia; Luxembourg Centre for Systems Biomedicine, University of Luxembourg, Belvaux, Luxembourg. Electronic address: alexander.mazein@uni.lu.
² European Institute for Systems Biology and Medicine, Université de Lyon, Lyon, France; Vrije Universiteit Amsterdam, Amsterdam, The Netherlands; Respiratory Medicine, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands.
³ European Institute for Systems Biology and Medicine, Université de Lyon, Lyon, France.
⁴ Luxembourg Centre for Systems Biomedicine, University of Luxembourg, Belvaux, Luxembourg.
⁵ Moscow Institute of Physics and Technology, Dolgoprudny, Moscow, Russia.
⁶ Faculty of Physics and Center for NanoScience (CeNS), Ludwig-Maximilians-Universität, Munich, Germany.
⁷ Institute of Computational Biology, Helmholtz Zentrum München, Neuherberg, Germany; Faculty of Mathematics and Natural Sciences, University of Bonn, Endenicher, Bonn, Germany.
⁸ Center for Regenerative Therapies Dresden (CRTD), Technische Universität Dresden, Dresden, Germany; German Center for Neurodegenerative Diseases (DZNE) Dresden, Dresden, Germany.
⁹ Knowles Consulting, Stevenage Bioscience Catalyst, Stevenage, United Kingdom.
¹⁰ Division of Physiological Chemistry 2, Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden.
¹¹ Unit for Experimental Asthma and Allergy Research, Institute of Environmental Medicine (IMM), Karolinska Institutet, Solna, Sweden.
¹² National Heart & Lung Institute, Imperial College London, London, United Kingdom.
¹³ Clinical and Experimental Sciences and Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, United Kingdom; NIHR Southampton Biomedical Research Centre, Southampton, United Kingdom.
¹⁴ Clinical and Experimental Sciences, University of Southampton Faculty of Medicine, University of Southampton, Southampton, United Kingdom; NIHR Southampton Respiratory Biomedical Research Unit, Southampton University Hospital, Southampton, United Kingdom.
¹⁵ Respiratory Medicine, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands.

PMID: 33309742
DOI: 10.1016/j.jaci.2020.11.032

No abstract available

Keywords: Asthma; data interpretation; disease map; disease mechanisms; knowledge representation.

Publication types

Editorial
Research Support, Non-U.S. Gov't

MeSH terms

Asthma / genetics
Asthma / immunology
Asthma / metabolism*
B-Lymphocytes / immunology*
Cell Communication
Eicosanoids / metabolism
Eosinophils / immunology*
Europe
Humans
Knowledge Bases
Mast Cells / immunology*
Respiratory Mucosa / physiology*
Software*
T-Lymphocytes / immunology*

Substances

Eicosanoids