Effect of Sickle Cell Trait and APOL1 Genotype on the Association of Soluble uPAR with Kidney Function Measures in Black Americans

Clin J Am Soc Nephrol. 2021 Feb 8;16(2):287-289. doi: 10.2215/CJN.12100720. Epub 2020 Dec 2.
No abstract available

Keywords: chronic kidney disease; clinical epidemiology; genetic renal disease; sickle cell trait.

Publication types

  • Letter
  • Research Support, N.I.H., Extramural

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Albuminuria / urine
  • Apolipoprotein L1 / genetics*
  • Black or African American
  • Creatinine / urine
  • Female
  • Genotype
  • Glomerular Filtration Rate
  • Humans
  • Incidence
  • Kidney / physiopathology*
  • Longitudinal Studies
  • Male
  • Middle Aged
  • Receptors, Urokinase Plasminogen Activator / blood*
  • Renal Insufficiency, Chronic / ethnology
  • Renal Insufficiency, Chronic / physiopathology*
  • Renal Insufficiency, Chronic / urine
  • Risk Factors
  • Sickle Cell Trait / physiopathology*
  • Young Adult

Substances

  • APOL1 protein, human
  • Apolipoprotein L1
  • Receptors, Urokinase Plasminogen Activator
  • Creatinine