Bilateral Silicone Granulomas Mimicking Breast Cancer Recurrence on 18F-FDG PET/CT

Victor Fernandes Vieira; Estelle Dubruc; Wassim Raffoul; John O Prior; Marie Meyer

doi:10.1097/RLU.0000000000003422

Bilateral Silicone Granulomas Mimicking Breast Cancer Recurrence on 18F-FDG PET/CT

Clin Nucl Med. 2021 Feb 1;46(2):140-141. doi: 10.1097/RLU.0000000000003422.

Authors

Victor Fernandes Vieira¹, Estelle Dubruc², Wassim Raffoul³, John O Prior¹, Marie Meyer¹

Affiliations

¹ From the Nuclear Medicine and Molecular Imaging Department.
² Pathology Department.
³ Plastic Surgery Department, Lausanne University Hospital, Lausanne, Switzerland.

PMID: 33234930
DOI: 10.1097/RLU.0000000000003422

Abstract

We report the case of a 45-year-old woman with a history of right breast reconstruction with silicone implant for breast cancer. An 18F-FDG PET/CT performed several years later revealed the presence of 18F-FDG-avid nodules at the periphery of the silicone implant, in the right internal mammary chain, and in the contralateral breast. Needle core biopsies were positive for bilateral silicone granulomas, without any sign of malignancy. This case displays intense 18F-FDG uptake in silicone granulomas affecting the contralateral breast after implant reconstruction.

Publication types

Case Reports

MeSH terms

Breast / pathology
Breast Neoplasms / diagnostic imaging*
Diagnosis, Differential
Female
Fluorodeoxyglucose F18
Granuloma / chemically induced*
Granuloma / diagnostic imaging*
Humans
Middle Aged
Positron Emission Tomography Computed Tomography*
Recurrence
Silicones / adverse effects*

Substances

Silicones
Fluorodeoxyglucose F18