Cement-augmented screw fixation for calcaneal fracture treatment: a biomechanical study comparing two injectable bone substitutes

J Orthop Surg Res. 2020 Nov 14;15(1):533. doi: 10.1186/s13018-020-02009-6.

Abstract

Background: The role of cement-augmented screw fixation for calcaneal fracture treatment remains unclear. Therefore, this study was performed to biomechanically analyze screw osteosynthesis by reinforcement with either a calcium phosphate (CP)-based or polymethylmethacrylate (PMMA)-based injectable bone cement.

Methods: A calcaneal fracture (Sanders type IIA) including a central cancellous bone defect was generated in 27 synthetic bones, and the specimens were assigned to 3 groups. The first group was fixed with four screws (3.5 mm and 6.5 mm), the second group with screws and CP-based cement (Graftys® QuickSet; Graftys, Aix-en-Provence, France), and the third group with screws and PMMA-based cement (Traumacem™ V+; DePuy Synthes, Warsaw, IN, USA). Biomechanical testing was conducted to analyze peak-to-peak displacement, total displacement, and stiffness in following a standardized protocol.

Results: The peak-to-peak displacement under a 200-N load was not significantly different among the groups; however, peak-to-peak displacement under a 600- and 1000-N load as well as total displacement exhibited better stability in PMMA-augmented screw osteosynthesis compared to screw fixation without augmentation. The stiffness of the construct was increased by both CP- and PMMA-based cements.

Conclusion: Addition of an injectable bone cement to screw osteosynthesis is able to increase fixation strength in a biomechanical calcaneal fracture model with synthetic bones. In such cases, PMMA-based cements are more effective than CP-based cements because of their inherently higher compressive strength. However, whether this high strength is required in the clinical setting for early weight-bearing remains controversial, and the non-degradable properties of PMMA might cause difficulties during subsequent interventions in younger patients.

Keywords: Arthritis; Bone; Calcaneus; Cement; Fixation; Fracture; Osteoporosis; Sanders; Screw.

Publication types

  • Comparative Study

MeSH terms

  • Biomechanical Phenomena*
  • Bone Cements*
  • Bone Screws*
  • Bone Substitutes / administration & dosage*
  • Calcaneus / injuries*
  • Calcium Phosphates / administration & dosage*
  • Fracture Fixation, Internal / methods*
  • Fractures, Bone / surgery*
  • Humans
  • Injections, Intralesional
  • Models, Anatomic
  • Polymethyl Methacrylate / administration & dosage*

Substances

  • Bone Cements
  • Bone Substitutes
  • Calcium Phosphates
  • Polymethyl Methacrylate
  • calcium phosphate

Grants and funding