Case 35-2020: A 59-Year-Old Woman with Type 1 Diabetes Mellitus and Obtundation

N Engl J Med. 2020 Nov 12;383(20):1974-1983. doi: 10.1056/NEJMcpc2002412.

Authors

David N Caplan¹, Otto Rapalino¹, Amel Karaa¹, Rachel P Rosovsky¹, Sacha Uljon¹

Affiliation

¹ From the Departments of Neurology (D.N.C.), Radiology (O.R.), Pediatrics (A.K.), Medicine (R.P.R.), and Pathology (S.U.), Massachusetts General Hospital, and the Departments of Neurology (D.N.C.), Radiology (O.R.), Pediatrics (A.K.), Medicine (R.P.R.), and Pathology (S.U.), Harvard Medical School - both in Boston.

PMID: 33176089
DOI: 10.1056/NEJMcpc2002412

No abstract available

Publication types

Case Reports

MeSH terms

Brain / diagnostic imaging
Brain / pathology
Ceruloplasmin / analysis*
Ceruloplasmin / deficiency*
Chelation Therapy
Cognitive Dysfunction / etiology
Diabetes Mellitus, Type 1 / complications*
Diagnosis, Differential
Female
Ferritins / blood
Humans
Iron Metabolism Disorders / complications
Iron Metabolism Disorders / diagnosis*
Iron Metabolism Disorders / therapy
Magnetic Resonance Imaging
Middle Aged
Neurodegenerative Diseases / complications
Neurodegenerative Diseases / diagnosis*
Neurodegenerative Diseases / therapy
Unconsciousness / etiology

Substances

Ferritins
Ceruloplasmin

Supplementary concepts

Familial apoceruloplasmin deficiency