Vestibulospinal pathway in rabbit includes GABA-synthesizing neurons

Neurosci Lett. 1987 Sep 23;80(2):158-62. doi: 10.1016/0304-3940(87)90646-x.

Abstract

When Fast blue is injected into the rabbit spinal cord it is retrogradely transported into nerve cell bodies located in the medial and the descending vestibular nuclei. Approximately 50% of the Fast blue-positive cells also contain glutamic acid decarboxylase-like immunoreactivity. These neurons presumably synthesize gamma-aminobutyric acid (GABA) and the rabbit vestibulospinal pathway therefore contains a substantial inhibitory component.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amidines
  • Animals
  • Fluorescent Antibody Technique
  • Glutamate Decarboxylase / analysis
  • Immunohistochemistry
  • Male
  • Neural Pathways / analysis
  • Neural Pathways / cytology
  • Neurons / classification
  • Neurons / enzymology
  • Rabbits
  • Spinal Cord / analysis*
  • Spinal Cord / cytology
  • Vestibular Nuclei / analysis*
  • Vestibular Nuclei / cytology
  • gamma-Aminobutyric Acid / metabolism
  • gamma-Aminobutyric Acid / physiology*

Substances

  • Amidines
  • diamidino compound 253-50
  • gamma-Aminobutyric Acid
  • Glutamate Decarboxylase