Bilateral acute retinal necrosis with encephalitis in a premature infant

Eur J Ophthalmol. 2022 Jan;32(1):NP185-NP186. doi: 10.1177/1120672120972023. Epub 2020 Nov 5.

Abstract

Introduction: Neonatal herpes infections can be extremely severe and their early recognition allows for appropriate management and increases the child's chances of survival.

Case description: We report the case of a premature infant born by vaginal delivery and transferred to intensive care after neonatal misadaptation. Examination of the fundus revealed lesions of acute bilateral retinal necrosis, strongly suggesting a herpetic etiology.

Conclusions: This case highlights the clinical benefit of an ophthalmologic exam in newborns with equivocal brain lesions. Herein, the fundus examination allowed for high suspicion of herpes virus infection.

Keywords: Neuro ophthalmology; acute retinal necrosis; herpes disease; infectious disease; pediatric ophthalmology.

Publication types

  • Case Reports

MeSH terms

  • Child
  • Encephalitis, Herpes Simplex*
  • Female
  • Herpes Simplex*
  • Humans
  • Infant
  • Infant, Newborn
  • Infant, Premature
  • Infant, Premature, Diseases*
  • Retinal Necrosis Syndrome, Acute* / diagnosis
  • Retinal Necrosis Syndrome, Acute* / drug therapy