Clinical Outcomes of Acute Myocardial Infarction Patients With a History of Malignant Tumor

In Vivo. 2020 Nov-Dec;34(6):3589-3595. doi: 10.21873/invivo.12203.

Abstract

Background: Little is known about the clinical outcomes of acute myocardial infarction (AMI) in patients with a history of malignant tumor (MT).

Patients and methods: We retrospectively studied 1,295 consecutive patients with AMI who underwent primary percutaneous coronary intervention within 24 hours of onset. The patients were divided into two groups: those with a history of MT (MT group, n=50) and those without (non-MT group, n=1,245).

Results: The MT group was older, and had lower hemoglobin, total protein, and albumin levels. All-cause mortality and re-admission rates due to acute decompensated heart failure (ADHF) were significantly higher in the MT group. Multivariate analysis showed that a history of MT was an independent predictor for all-cause mortality and re-admission due to ADHF.

Conclusion: The clinical outcomes of patients with AMI with a history of MT are poor, and a history of MT is an independent predictor for all-cause mortality and re-admission due to ADHF. These patients may need careful risk management for heart failure to avoid re-admissions due to ADHF.

Keywords: Malignant tumor; acute myocardial infarction; heart failure.

MeSH terms

  • Heart Failure* / epidemiology
  • Humans
  • Myocardial Infarction* / epidemiology
  • Myocardial Infarction* / therapy
  • Neoplasms*
  • Percutaneous Coronary Intervention*
  • Retrospective Studies