How reliable and useful is the latex agglutination test in diagnosing streptococcal throat infection in general practice?

Scand J Prim Health Care. 1987 Sep;5(3):151-4. doi: 10.3109/02813438709013996.

Abstract

A rapid latex agglutination test for diagnosing streptococcal pharyngitis in general practice was evaluated on 226 patients with acute throat infection. The test had a sensitivity of 96% and a specificity of 91% regarding group A beta hemolytic streptococci. The test was fairly simple to perform and the result was available before the patient left the office. The test was supplied as a self-contained kit, was safe to handle and economically acceptable. Even through this test is not a reliable as the traditional microbiological culture, it represents a significant practical and clinical improvement in the daily management of patients with acute throat infections.

MeSH terms

  • Family Practice*
  • Humans
  • Latex Fixation Tests / standards*
  • Pharyngitis / microbiology*
  • Reagent Kits, Diagnostic
  • Streptococcal Infections / microbiology*
  • Streptococcus pyogenes / isolation & purification

Substances

  • Reagent Kits, Diagnostic