1 Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, CA, USA.
2 Institute for Human Genetics, University of California, San Francisco, San Francisco, CA, USA.
3 Biological and Medical Informatics Graduate Program, University of California, San Francisco, San Francisco, CA, USA.
4 Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, CA, USA. fumitaka.inoue@ucsf.edu.
5 Institute for Human Genetics, University of California, San Francisco, San Francisco, CA, USA. fumitaka.inoue@ucsf.edu.
6 Berlin Institute of Health (BIH), Berlin, Germany.
7 Department of Genome Sciences, University of Washington, Seattle, WA, USA.
8 Calico Life Sciences LLC, South San Francisco, CA, USA.
9 Gladstone Institutes, San Francisco, CA, USA.
10 Department of Electrical Engineering and Computer Sciences and Center for Computational Biology, University of California, Berkeley, Berkeley, CA, USA.
11 Chan-Zuckerberg Biohub, San Francisco, CA, USA.
12 Division of Rheumatology, Department of Medicine, University of California, San Francisco, San Francisco, CA, USA.
13 Institute for Computational Health Sciences, University of California, San Francisco, San Francisco, California, USA.
14 Department of Epidemiology and Biostatistics and Institute of Computational Health Sciences, University of California, San Francisco, San Francisco, CA, USA.
15 Department of Genome Sciences, University of Washington, Seattle, WA, USA. shendure@uw.edu.
16 Howard Hughes Medical Institute, Seattle, WA, USA. shendure@uw.edu.
17 Brotman Baty Institute for Precision Medicine, University of Washington, Seattle, WA, USA. shendure@uw.edu.
18 Berlin Institute of Health (BIH), Berlin, Germany. martin.kircher@bihealth.de.