We present the case of a severe and long-standing Dupuytren's contracture where intraoperatively an ossified nodule was encountered within the diseased tissue. Histologically palmar fibromatosis in contact with cartilaginous tissue with central ossification could be confirmed, compatible with metaplasia. Our finding suggests that metaplastic activity inherent to longstanding, severely diseased Dupuytren's tissue can lead to heterotopic ossification.
Keywords: Dupuytren contracture; Heterotopic ossification; Metaplasia.