Zoonotic infection with swine A/H1avN1 influenza virus in a child, Germany, June 2020

Euro Surveill. 2020 Oct;25(42):2001638. doi: 10.2807/1560-7917.ES.2020.25.42.2001638.

Abstract

A zoonotic A/sw/H1avN1 1C.2.2 influenza virus infection was detected in a German child that presented with influenza-like illness, including high fever. There was a history of close contact with pigs 3 days before symptom onset. The child recovered within 3 days. No other transmissions were observed. Serological investigations of the virus isolate revealed cross-reactions with ferret antisera against influenza A(H1N1)pdm09 virus, indicating a closer antigenic relationship with A(H1N1)pdm09 than with the former seasonal H1N1 viruses.

Keywords: Germany; epidemiology; influenza; influenza virus; laboratory; sentinel surveillance; viral infections; zoonotic infections.

Publication types

  • Case Reports

MeSH terms

  • Animals
  • Antibodies, Viral / blood
  • Antigenic Variation / genetics*
  • Antigenic Variation / immunology
  • Ferrets / virology*
  • Hemagglutinin Glycoproteins, Influenza Virus / genetics*
  • Hemagglutinin Glycoproteins, Influenza Virus / immunology
  • Humans
  • Influenza A Virus, H1N1 Subtype / classification
  • Influenza A Virus, H1N1 Subtype / genetics*
  • Influenza A Virus, H1N1 Subtype / isolation & purification
  • Influenza, Human / diagnosis*
  • Influenza, Human / transmission
  • Influenza, Human / virology
  • Orthomyxoviridae Infections / diagnosis*
  • Orthomyxoviridae Infections / transmission
  • Orthomyxoviridae Infections / veterinary
  • Orthomyxoviridae Infections / virology
  • Polymerase Chain Reaction
  • Sequence Analysis
  • Swine
  • Swine Diseases / transmission*
  • Swine Diseases / virology
  • Zoonoses / transmission
  • Zoonoses / virology*

Substances

  • Antibodies, Viral
  • Hemagglutinin Glycoproteins, Influenza Virus