Use of Immunotherapy in Patients With Cancer During the COVID-19 Pandemic

Oncology (Williston Park). 2020 Sep 15;34(9):370-376. doi: 10.46883/ONC.2020.3409.0370.

Abstract

In an asymptomatic 77-yearold woman, former 55 packyears smoker, a routine X-ray showed a 45-mm superior left lobe lesion. A chest CT scan confirmed a 36-mm superior left lobe lesion and an aortic-pulmonary lymph node enlargement measuring 42 mm, suspicious for neoplasia. A PET-CT scan showed an elevated uptake in the primary lesion, in the aortic-pulmonary lymph node, and in the left hilar lymph node with a standardized uptake value - 40 and 4.3, respectively. CT-guided lung biopsy showed a lung squamous cell carcinoma. An endobronchial ultrasound-guided transbronchial needle aspiration for lymph-node staging was negative for lymph node spread. Brain MRI was negative. Final staging was determined to be a IIIA (T2bN2) squamous cell carcinoma of the lung.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Antibodies, Monoclonal / adverse effects
  • Antibodies, Monoclonal / therapeutic use*
  • Antineoplastic Agents, Immunological / adverse effects
  • Antineoplastic Agents, Immunological / therapeutic use*
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Betacoronavirus
  • COVID-19
  • Carboplatin / administration & dosage
  • Carcinoma, Squamous Cell / diagnostic imaging
  • Carcinoma, Squamous Cell / therapy*
  • Chemoradiotherapy
  • Consolidation Chemotherapy
  • Coronavirus Infections / diagnosis*
  • Diagnosis, Differential
  • Female
  • Humans
  • Lung / diagnostic imaging
  • Lung Neoplasms / diagnostic imaging
  • Lung Neoplasms / therapy*
  • Paclitaxel / administration & dosage
  • Pandemics
  • Pneumonia / chemically induced
  • Pneumonia / diagnosis*
  • Pneumonia, Viral / diagnosis*
  • SARS-CoV-2

Substances

  • Antibodies, Monoclonal
  • Antineoplastic Agents, Immunological
  • durvalumab
  • Carboplatin
  • Paclitaxel