Investigation of the frequency of COVID-19 in patients treated with intravesical BCG

Rev Assoc Med Bras (1992). 2020 Sep 21;66Suppl 2(Suppl 2):91-95. doi: 10.1590/1806-9282.66.S2.91. eCollection 2020.

Abstract

Introduction: In this retrospective study, we aimed to investigate the frequency of COVID-19 in patients with and without BCG application due to bladder tumors.

Methods: The presence of COVID-19 was investigated in 167 patients with BCG and 167 without bladder cancer. All patients were compatible with COVID-19 infection. Patients with RT-PCR positive for SARS-CoV-2 and/or Chest CT positive for viral pneumonia between March and May 2020 were included in the study.

Results: A total of 334 patients were included in the study. The mean age of the 167 patients in the study group was 71.1±14.2 1 (min. 38.0- max. 98.0 years), 141 (84.4%) were male. The mean age of the 167 patients in the control group was 70.5±13.8 years (min. 41.0- max. 96.0 years), and 149 were male (p> 0.05). COVID-19 was detected in 5 patients in the BCG group and in 4 patients in the control group (P> 0.05).

Conclusion: Intravesical BCG administration does not decrease the frequency of COVID-19 infection.

MeSH terms

  • Aged
  • Aged, 80 and over
  • BCG Vaccine / administration & dosage
  • BCG Vaccine / adverse effects*
  • Betacoronavirus*
  • COVID-19
  • Coronavirus Infections / epidemiology*
  • Humans
  • Male
  • Middle Aged
  • Pandemics*
  • Pneumonia, Viral / epidemiology*
  • Retrospective Studies
  • SARS-CoV-2

Substances

  • BCG Vaccine