1 Department of Cardiovascular Sciences, National Institute for Health Research Leicester Biomedical Research Unit in Cardiovascular Medicine, UK. Electronic address: mr345@le.ac.uk.
2 Department of Cardiovascular Sciences, National Institute for Health Research Leicester Biomedical Research Unit in Cardiovascular Medicine, UK.
3 Biostatistics Research Group, Department of Health Sciences, College of Life Sciences, University of Leicester, Leicester, UK.