1 , , , , , , , , , , , and , University College Dublin, Belfield; , , , and , Royal College of Surgeons in Ireland; , , , , , , and , Mater Misericordiae University Hospital; , Beaumont Hospital, Dublin, Ireland; and , Vrije Universiteit Medical Center, Amsterdam, the Netherlands; and , Vesailus Research Center, Vlaams Instituut voor Biotechnologie, Katholieke Universiteit, Leuven, Belgium.