Prospective Evaluation of a Standardized Opioid Reduction Protocol after Anorectal Surgery

J Surg Res. 2020 Dec:256:564-569. doi: 10.1016/j.jss.2020.07.028. Epub 2020 Aug 14.

Abstract

Background: Surgery for anorectal disease is thought to cause significant postoperative pain. Our previous work demonstrated that most opioids prescribed after anorectal surgery are not used. We aimed to evaluate a standardized protocol for pain control after anorectal surgery.

Methods: We prospectively evaluated a standardized opioid reduction protocol over a 13-mo period for all patients undergoing elective anorectal surgery at our institution. Protocol components include preoperative query, procedural local-anesthetic blocks, first-line nonopioid analgesic use ± opioid prescription of five pills, and standardized postoperative instructions. Patients completed questionnaires at postoperative follow-up. Patients with history of opioid abuse or use within 30 d of operation, loss to follow-up, or surgical complications were excluded. Primary outcome was quality of pain control on a five-point scale. Secondary outcomes included use of nonopioid analgesics, opioids used, and need for refill.

Results: A total of 55 patients were included. Mean age was 47 ± 17 y with 23 women (42%). Anorectal abscess/fistula procedures were the most common (69%) followed by pilonidal procedures (11%) and hemorrhoidectomy (7%). Most had general anesthesia (60%) with the remainder local anesthesia ± sedation. Fifty-four (98%) had procedural local-anesthetic blocks. Twenty-six patients (47%) were prescribed opioids with a median of five pills. Forty-seven patients (85%) reported the use of nonopioid analgesics. Forty-six patients (84%) reported excellent to very good pain control. About 220 opioid pills were prescribed, and 122 were reported to be used. One patient (2%) received an opioid refill.

Conclusions: Satisfactory pain control after anorectal surgery can be achieved with multimodality therapy with little to no opioid use for most patients.

Keywords: Anorectal; Opioid; Opioid reduction.

Publication types

  • Observational Study

MeSH terms

  • Adult
  • Analgesics, Non-Narcotic / administration & dosage
  • Analgesics, Opioid / adverse effects*
  • Anesthesia, General / standards
  • Anesthesia, General / statistics & numerical data
  • Anesthesia, Local / standards
  • Anesthesia, Local / statistics & numerical data
  • Combined Modality Therapy / methods
  • Combined Modality Therapy / standards
  • Combined Modality Therapy / statistics & numerical data
  • Drug Prescriptions / statistics & numerical data
  • Elective Surgical Procedures / adverse effects*
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Middle Aged
  • Nerve Block / standards
  • Nerve Block / statistics & numerical data
  • Pain Management / methods
  • Pain Management / standards*
  • Pain Management / statistics & numerical data
  • Pain Measurement
  • Pain, Postoperative / diagnosis
  • Pain, Postoperative / etiology
  • Pain, Postoperative / therapy*
  • Practice Patterns, Physicians' / standards
  • Practice Patterns, Physicians' / statistics & numerical data
  • Prospective Studies
  • Rectal Diseases / surgery*
  • Treatment Outcome

Substances

  • Analgesics, Non-Narcotic
  • Analgesics, Opioid