The unprecedented pandemic events that currently affect animals and humans have fueled calls for One Health action. We argue that the One Health framework must be accompanied by ‘rich outcomes’ to avoid a reductionist One Health focus on zoonotic pathogens, that forgoes the benefits of the framework. We propose that the United Nation’s sustainable development goals provide an adequate multidimensional set of targets that can help researchers and policymakers contextualise emerging diseases, and guide One Health long‐term solutions that are equitable, efficacious, and sustainable.