The changing face of paracetamol toxicity and new regimens for an old antidote acetylcysteine

Br J Clin Pharmacol. 2021 Mar;87(3):715-716. doi: 10.1111/bcp.14495. Epub 2020 Aug 3.

Authors

Geoffrey K Isbister¹, Angela Chiew^{2

3}

Affiliations

¹ Clinical Toxicology Research Group, University of Newcastle, Waratah, New South Wales, Australia.
² NSW Poisons Information Centre, Children's Hospital at Westmead, Westmead, New South Wales, Australia.
³ Department of Pharmacology, School of Medical Sciences, University of Sydney, Sydney, New South Wales, Australia.

PMID: 32748454
DOI: 10.1111/bcp.14495

No abstract available

Keywords: acetylcysteine; antidote; clinical toxicology; overdose and poisoning; paracetamol.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Acetaminophen / adverse effects
Acetylcysteine / adverse effects
Analgesics, Non-Narcotic* / adverse effects
Antidotes / adverse effects
Drug Overdose* / drug therapy
Humans

Substances

Analgesics, Non-Narcotic
Antidotes
Acetaminophen
Acetylcysteine

Grants and funding

1154503/Australian National Health and Medical Research Council Senior Research Fellowship